Just when life seemed to return to normal, two new COVID-19 variants have made a global entrance in 2025.
Nicknamed “Frankenstein” (XFG) and “Nimbus” (NB.1.8.1), these variants are raising eyebrows not just for their catchy names but for their rapid spread and unique symptoms. Should we worry? Are vaccines still effective? What do we need to prepare for? Let’s dive into the facts.
XFG Variant (Stratus / Frankenstein)
- Lineage: A recombinant of two Omicron strains—LF.7 and LP.8.1.2.
- Mutation profile: Over 9 additional spike protein mutations compared to previous strains.
- Spread: Dominant in the UK (40%+), also growing in Ireland and the EU.
- Risk: Fortunately, studies show that JN.1-based vaccines still offer protection, and antivirals like Paxlovid remain effective.
NB.1.8.1 Variant (Nimbus)
- Known for: The infamous “razor blade throat” sensation—intense sore throats that are commonly reported.
- Prevalence: Found in 20+ countries, particularly prevalent in the U.S., China, Japan, and Europe.
- Risk level: More infectious, but not appear more deadly. Vaccinated individuals still show protection against severe illness.
How to Stay Protected
Stay Updated on Vaccines
- JN.1-based boosters remain key tools in preventing serious illness.
- High-risk individuals are advised to get boosters every 3 months.
Stick to the Basics
- Hand hygiene, masking in crowded spaces, and indoor ventilation are still crucial in controlling spread.
Act Fast if You Have Symptoms
- If you develop sore throat, fever, or fatigue, test immediately and isolate if necessary.
Yes, the names sound dramatic. But in 2025, we’re not the same as in 2020. We’re better prepared, more informed, and scientifically equipped. COVID-19 may continue to mutate, but so will our resilience and response. Let’s stay cautious, not fearful—and move forward, responsibly.
